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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XRCC1 All Species: 6.67
Human Site: T257 Identified Species: 14.67
UniProt: P18887 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18887 NP_006288 633 69526 T257 L N Q E E K K T P S K P P A Q
Chimpanzee Pan troglodytes XP_512717 596 65689 P241 K R P K L P A P T R T P A T A
Rhesus Macaque Macaca mulatta XP_001100256 645 69984 T299 I N K T S P V T A S D P A G P
Dog Lupus familis XP_533653 654 71801 T280 L N Q E E R K T P S K P S A Q
Cat Felis silvestris
Mouse Mus musculus Q60596 631 68952 P259 L S L E D R K P P S K P S A G
Rat Rattus norvegicus Q9ESZ0 631 68817 P259 L G L E D K K P P S K P S A G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516926 549 59237 S218 K P P P S S S S S S S S N K V
Chicken Gallus gallus
Frog Xenopus laevis NP_001080711 651 73244 K266 T V K K P E V K E S P S S T K
Zebra Danio Brachydanio rerio NP_001003988 615 68071 A256 L E A S G P P A K K P S S S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572217 614 68751 L256 R S V S P T P L D A K P L D R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001180271 512 56847 E180 D A D K K E G E N S H K R P A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.8 82.3 86 N.A. 86 86.5 N.A. 47.7 N.A. 53.9 51.1 N.A. 20.7 N.A. N.A. 38.8
Protein Similarity: 100 94.1 83 88.3 N.A. 91.1 91 N.A. 56.5 N.A. 67.7 68.8 N.A. 36.9 N.A. N.A. 55.1
P-Site Identity: 100 6.6 26.6 86.6 N.A. 53.3 60 N.A. 6.6 N.A. 6.6 6.6 N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 13.3 40 93.3 N.A. 73.3 66.6 N.A. 13.3 N.A. 33.3 13.3 N.A. 33.3 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 0 0 10 10 10 10 0 0 19 37 28 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 10 0 19 0 0 0 10 0 10 0 0 10 0 % D
% Glu: 0 10 0 37 19 19 0 10 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 10 0 10 0 0 0 0 0 0 10 19 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 19 0 19 28 10 19 37 10 10 10 46 10 0 10 10 % K
% Leu: 46 0 19 0 10 0 0 10 0 0 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 28 0 0 0 0 0 0 10 0 0 0 10 0 0 % N
% Pro: 0 10 19 10 19 28 19 28 37 0 19 64 10 10 10 % P
% Gln: 0 0 19 0 0 0 0 0 0 0 0 0 0 0 19 % Q
% Arg: 10 10 0 0 0 19 0 0 0 10 0 0 10 0 10 % R
% Ser: 0 19 0 19 19 10 10 10 10 73 10 28 46 10 0 % S
% Thr: 10 0 0 10 0 10 0 28 10 0 10 0 0 19 0 % T
% Val: 0 10 10 0 0 0 19 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _